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Coincident Activation of Glutamate Receptors Enhances GABA(A) Receptor-Induced Ionic Plasticity of the Intracellular Cl(−)-Concentration in Dissociated Neuronal Cultures
Massive activation of γ-amino butyric acid A (GABA(A)) receptors during pathophysiological activity induces an increase in the intracellular Cl(−)-concentration ([Cl(−)](i)), which is sufficient to render GABAergic responses excitatory. However, to what extent physiological levels of GABAergic activ...
Autores principales: | Halbhuber, Lisa, Achtner, Cécilia, Luhmann, Heiko J., Sinning, Anne, Kilb, Werner |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856009/ https://www.ncbi.nlm.nih.gov/pubmed/31787883 http://dx.doi.org/10.3389/fncel.2019.00497 |
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