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P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease
Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. Taking into account that adenosine-5’-triphosphate (ATP) and its metabolites are intensely released in the 6-hydroxydopamine (6-OHDA) animal model of...
Autores principales: | Oliveira-Giacomelli, Ágatha, M. Albino, Carolina, de Souza, Hellio Danny Nóbrega, Corrêa-Velloso, Juliana, de Jesus Santos, Ana Paula, Baranova, Juliana, Ulrich, Henning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856016/ https://www.ncbi.nlm.nih.gov/pubmed/31787881 http://dx.doi.org/10.3389/fncel.2019.00476 |
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