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Dynamics of Prolyl Hydroxylases Levels During Disease Progression in Experimental Colitis

Hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) inhibitors are shown to be protective in several models of inflammatory bowel disease (IBD). However, these non-selective inhibitors are known to inhibit all the three isoforms of PHD, i.e. PHD-1, PHD-2 and PHD-3. In the present report, we inve...

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Detalles Bibliográficos
Autores principales: Bakshi, Hamid A., Mishra, Vijay, Satija, Saurabh, Mehta, Meenu, Hakkim, Faruk L., Kesharwani, Prashant, Dua, Kamal, Chellappan, Dinesh K., Charbe, Nitin B., Shrivastava, Garima, Rajeshkumar, S., Aljabali, Alaa A., Al-Trad, Bahaa, Pabreja, Kavita, Tambuwala, Murtaza M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856031/
https://www.ncbi.nlm.nih.gov/pubmed/31377947
http://dx.doi.org/10.1007/s10753-019-01065-3