Identification of candidate molecular targets of the novel antineoplastic antimitotic NP-10

We previously reported the identification of a novel antimitotic agent with carbazole and benzohydrazide structures: N′-[(9-ethyl-9H-carbazol-3-yl)methylene]-2-iodobenzohydrazide (code number NP-10). However, the mechanism(s) underlying the cancer cell-selective inhibition of mitotic progression by...

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Detalles Bibliográficos
Autores principales: Yokoyama, Takuya, Yukuhiro, Masaki, Iwasaki, Yuka, Tanaka, Chika, Sankoda, Kazunari, Fujiwara, Risa, Shibuta, Atsushi, Higashi, Taishi, Motoyama, Keiichi, Arima, Hidetoshi, Yoshida, Kazumasa, Sugimoto, Nozomi, Morimoto, Hiroyuki, Kosako, Hidetaka, Ohshima, Takashi, Fujita, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856148/
https://www.ncbi.nlm.nih.gov/pubmed/31727981
http://dx.doi.org/10.1038/s41598-019-53259-2

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