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A human expression system based on HEK293 for the stable production of recombinant erythropoietin
Mammalian host cell lines are the preferred expression systems for the manufacture of complex therapeutics and recombinant proteins. However, the most utilized mammalian host systems, namely Chinese hamster ovary (CHO), Sp2/0 and NS0 mouse myeloma cells, can produce glycoproteins with non-human glyc...
Autores principales: | Chin, Christine Lin, Goh, Justin Bryan, Srinivasan, Harini, Liu, Kaiwen Ivy, Gowher, Ali, Shanmugam, Raghuvaran, Lim, Hsueh Lee, Choo, Matthew, Tang, Wen Qin, Tan, Andy Hee-Meng, Nguyen-Khuong, Terry, Tan, Meng How, Ng, Say Kong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856173/ https://www.ncbi.nlm.nih.gov/pubmed/31727983 http://dx.doi.org/10.1038/s41598-019-53391-z |
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