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Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease

Alzheimer’s disease (AD), which is the most common type of dementia, is characterized by the deposition of extracellular amyloid plaques. To understand the pathophysiology of the AD brain, the assessment of global proteomic dynamics is required. Since the hippocampus is a major region affected in th...

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Detalles Bibliográficos
Autores principales:	Kim, Dong Kyu, Han, Dohyun, Park, Joonho, Choi, Hyunjung, Park, Jong-Chan, Cha, Moon-Yong, Woo, Jongmin, Byun, Min Soo, Lee, Dong Young, Kim, Youngsoo, Mook-Jung, Inhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856180/ https://www.ncbi.nlm.nih.gov/pubmed/31727875 http://dx.doi.org/10.1038/s12276-019-0326-z

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