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Heterologous Expression of a Cryptic Gene Cluster from Streptomyces leeuwenhoekii C34(T) Yields a Novel Lasso Peptide, Leepeptin

Analysis of the genome sequence of Streptomyces leeuwenhoekii C34(T) identified biosynthetic gene clusters (BGCs) for three different lasso peptides (Lp1, Lp2, and Lp3) which were not known to be made by the strain. Lasso peptides represent relatively new members of the RiPP (ribosomally synthesized...

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Detalles Bibliográficos
Autores principales:	Gomez-Escribano, Juan Pablo, Castro, Jean Franco, Razmilic, Valeria, Jarmusch, Scott A., Saalbach, Gerhard, Ebel, Rainer, Jaspars, Marcel, Andrews, Barbara, Asenjo, Juan A., Bibb, Mervyn J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genetics and Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856326/ https://www.ncbi.nlm.nih.gov/pubmed/31562169 http://dx.doi.org/10.1128/AEM.01752-19

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