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Metabolic gene alterations impact the clinical aggressiveness and drug responses of 32 human cancers
Malignant cells reconfigure their metabolism to support oncogenic processes such as accelerated growth and proliferation. The mechanisms by which this occurs likely involve alterations to genes that encode metabolic enzymes. Here, using genomics data for 10,528 tumours of 32 different cancer types,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856368/ https://www.ncbi.nlm.nih.gov/pubmed/31754644 http://dx.doi.org/10.1038/s42003-019-0666-1 |