Release from Unc93b1 reinforces the compartmentalized activation of select TLRs

Nucleic acid-sensing Toll-like receptors (TLRs) are subject to complex regulation to facilitate recognition of microbial DNA and RNA while limiting recognition of self-nucleic acids(1). Failure to properly regulate these TLRs can lead to autoimmune and autoinflammatory disease(2–6). Intracellular lo...

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Detalles Bibliográficos
Autores principales: Majer, Olivia, Liu, Bo, Woo, Brian J, Kreuk, Lieselotte SM, Van Dis, Erik, Barton, Gregory M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856438/
https://www.ncbi.nlm.nih.gov/pubmed/31546247
http://dx.doi.org/10.1038/s41586-019-1611-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856438/
https://www.ncbi.nlm.nih.gov/pubmed/31546247
http://dx.doi.org/10.1038/s41586-019-1611-7

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