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Absence of the neutrophil serine protease cathepsin G decreases neutrophil granulocyte infiltration but does not change the severity of acute pancreatitis

Acute pancreatitis is characterized by an early intracellular protease activation and invasion of leukocytes into the pancreas. Cathepsins constitute a large group of lysosomal enzymes, that have been shown to modulate trypsinogen activation and neutrophil infiltration. Cathepsin G (CTSG) is a neutr...

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Detalles Bibliográficos
Autores principales:	Aghdassi, Ali A., John, Daniel S., Sendler, Matthias, Storck, Christian, van den Brandt, Cindy, Krüger, Burkhard, Weiss, Frank Ulrich, Mayerle, Julia, Lerch, Markus M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856518/ https://www.ncbi.nlm.nih.gov/pubmed/31727956 http://dx.doi.org/10.1038/s41598-019-53293-0

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