17β-Estradiol Attenuates Neuropathic Pain Caused by Spared Nerve Injury by Upregulating CIC-3 in the Dorsal Root Ganglion of Ovariectomized Rats

17β-estradiol plays a role in pain sensitivity, analgesic drug efficacy, and neuropathic pain prevalence, but the underlying mechanisms remain unclear. Here, we investigated whether voltage-gated chloride channel-3 (ClC-3) impacts the effects of 17β-estradiol (E2) on spared nerve injury (SNI)-induce...

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Detalles Bibliográficos
Autores principales: Xu, Zhen-Zhen, Chen, Qin-Yi, Deng, Shi-Yu, Zhang, Meng, Tan, Chao-Yang, Yang Wang, Ma, Ke-Tao, Li, Li, Si, Jun-Qiang, Zhu, Li-Cang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856564/
https://www.ncbi.nlm.nih.gov/pubmed/31787875
http://dx.doi.org/10.3389/fnins.2019.01205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856564/
https://www.ncbi.nlm.nih.gov/pubmed/31787875
http://dx.doi.org/10.3389/fnins.2019.01205

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