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Structural and Functional Determinants of Rodent and Human Surfactant Protein A: A Synthesis of Binding and Computational Data

Surfactant protein A (SP-A) provides surfactant stability, first line host defense, and lung homeostasis by binding surfactant phospholipids, pathogens, alveolar macrophages (AMs), and epithelial cells. Non-primates express one SP-A protein whereas humans express two: SP-A1 and SP-A2 with core intra...

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Detalles Bibliográficos
Autores principales:	Nalian, Armen, Umstead, Todd M., Yang, Ching-Hui, Silveyra, Patricia, Thomas, Neal J., Floros, Joanna, McCormack, Francis X., Chroneos, Zissis C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2019
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856657/ https://www.ncbi.nlm.nih.gov/pubmed/31781112 http://dx.doi.org/10.3389/fimmu.2019.02613

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