Low Density Granulocytes in ANCA Vasculitis Are Heterogenous and Hypo-Responsive to Anti-Myeloperoxidase Antibodies

Low Density Granulocytes (LDGs), which appear in the peripheral blood mononuclear cell layer of density-separated blood, are seen in cancer, sepsis, autoimmunity, and pregnancy. Their significance in ANCA vasculitis (AAV) is little understood. As these cells bear the autoantigens associated with thi...

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Detalles Bibliográficos
Autores principales: Ui Mhaonaigh, Aisling, Coughlan, Alice M., Dwivedi, Amrita, Hartnett, Jack, Cabral, Joana, Moran, Barry, Brennan, Kiva, Doyle, Sarah L., Hughes, Katherine, Lucey, Rosemary, Floudas, Achilleas, Fearon, Ursula, McGrath, Susan, Cormican, Sarah, De Bhailis, Aine, Molloy, Eleanor J., Brady, Gareth, Little, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856659/
https://www.ncbi.nlm.nih.gov/pubmed/31781107
http://dx.doi.org/10.3389/fimmu.2019.02603

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