Single-Cell Transcriptomics Uncovers Zonation of Function in the Mesenchyme during Liver Fibrosis

Iterative liver injury results in progressive fibrosis disrupting hepatic architecture, regeneration potential, and liver function. Hepatic stellate cells (HSCs) are a major source of pathological matrix during fibrosis and are thought to be a functionally homogeneous population. Here, we use single...

Descripción completa

Detalles Bibliográficos
Autores principales: Dobie, Ross, Wilson-Kanamori, John R., Henderson, Beth E.P., Smith, James R., Matchett, Kylie P., Portman, Jordan R., Wallenborg, Karolina, Picelli, Simone, Zagorska, Anna, Pendem, Swetha V., Hudson, Thomas E., Wu, Minnie M., Budas, Grant R., Breckenridge, David G., Harrison, Ewen M., Mole, Damian J., Wigmore, Stephen J., Ramachandran, Prakash, Ponting, Chris P., Teichmann, Sarah A., Marioni, John C., Henderson, Neil C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856722/
https://www.ncbi.nlm.nih.gov/pubmed/31722201
http://dx.doi.org/10.1016/j.celrep.2019.10.024

Ejemplares similares

Ejemplares similares