Cargando…
In vitro education of human natural killer cells by KIR3DL1
During development, NK cells are “educated” to respond aggressively to cells with low surface expression of HLA class I, a hallmark of malignant and infected cells. The mechanism of education involves interactions between inhibitory killer immunoglobulin–like receptors (KIRs) and specific HLA epitop...
Autores principales: | Pugh, Jason, Nemat-Gorgani, Neda, Djaoud, Zakia, Guethlein, Lisbeth A, Norman, Paul J, Parham, Peter |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856763/ https://www.ncbi.nlm.nih.gov/pubmed/31723004 http://dx.doi.org/10.26508/lsa.201900434 |
Ejemplares similares
-
Abundant CpG-sequences in human genomes inhibit KIR3DL2-expressing NK cells
por: Pugh, Jason, et al.
Publicado: (2021) -
CD56-negative NK cells: Frequency in peripheral blood, expansion during HIV-1 infection, functional capacity, and KIR expression
por: Cocker, Alexander T. H., et al.
Publicado: (2022) -
Two alternate strategies for innate immunity to Epstein-Barr virus: One using NK cells and the other NK cells and γδ T cells
por: Djaoud, Zakia, et al.
Publicado: (2017) -
Natural LILRB1 D1-D2 variants show frequency differences in populations and bind to HLA class I with various avidities
por: Liu, Fuguo, et al.
Publicado: (2022) -
Conservation, Extensive Heterozygosity, and Convergence of Signaling Potential All Indicate a Critical Role for KIR3DL3 in Higher Primates
por: Leaton, Laura A., et al.
Publicado: (2019)