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MMP9 modulates the metastatic cascade and immune landscape for breast cancer anti-metastatic therapy
Metastasis, the main cause of cancer-related death, has traditionally been viewed as a late-occurring process during cancer progression. Using the MMTV-PyMT luminal B breast cancer model, we demonstrate that the lung metastatic niche is established early during tumorigenesis. We found that matrix me...
Autores principales: | Owyong, Mark, Chou, Jonathan, van den Bijgaart, Renske JE, Kong, Niwen, Efe, Gizem, Maynard, Carrie, Talmi-Frank, Dalit, Solomonov, Inna, Koopman, Charlotte, Hadler-Olsen, Elin, Headley, Mark, Lin, Charlene, Wang, Chih-Yang, Sagi, Irit, Werb, Zena, Plaks, Vicki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856766/ https://www.ncbi.nlm.nih.gov/pubmed/31727800 http://dx.doi.org/10.26508/lsa.201800226 |
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