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The structural and biochemical impacts of monomerizing human acetylcholinesterase

Serving a critical role in neurotransmission, human acetylcholinesterase (hAChE) is the target of organophosphate nerve agents. Hence, there is an active interest in studying the mechanism of inhibition and recovery of enzymatic activity, which could lead to better countermeasures against nerve agen...

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Detalles Bibliográficos
Autores principales:	Bester, Stephanie M., Adipietro, Kaylin A., Funk, Vanessa L., Myslinski, James M., Keul, Nicholas D., Cheung, Jonah, Wilder, Paul T., Wood, Zachary A., Weber, David J., Height, Jude J., Pegan, Scott D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2019
Materias:	Full‐Length Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856767/ https://www.ncbi.nlm.nih.gov/pubmed/30993792 http://dx.doi.org/10.1002/pro.3625

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