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Pathological analysis of cadavers for educational dissection by using postmortem imaging

This study was performed primarily to clarify whether pathological analysis of cadavers for anatomical dissection is possible using postmortem imaging (PMI), and whether this is worthwhile. A total of 33 cadavers that underwent systematic anatomical dissection at our medical school also underwent PM...

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Autores principales: Noriki, Sakon, Iino, Satoshi, Kinoshita, Kazuyuki, Fukazawa, Yugo, Inai, Kunihiro, Sakai, Toyohiko, Kimura, Hirohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856864/
https://www.ncbi.nlm.nih.gov/pubmed/31631464
http://dx.doi.org/10.1111/pin.12857
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author Noriki, Sakon
Iino, Satoshi
Kinoshita, Kazuyuki
Fukazawa, Yugo
Inai, Kunihiro
Sakai, Toyohiko
Kimura, Hirohiko
author_facet Noriki, Sakon
Iino, Satoshi
Kinoshita, Kazuyuki
Fukazawa, Yugo
Inai, Kunihiro
Sakai, Toyohiko
Kimura, Hirohiko
author_sort Noriki, Sakon
collection PubMed
description This study was performed primarily to clarify whether pathological analysis of cadavers for anatomical dissection is possible using postmortem imaging (PMI), and whether this is worthwhile. A total of 33 cadavers that underwent systematic anatomical dissection at our medical school also underwent PMI. Fixative solution was injected into the corpus 3–4 days after death. PMI was then performed using an 8‐slice multi‐detector CT scanner 3 months before dissection. Before dissection, a conference was held to discuss the findings of the PMI. First, two radiologists read the postmortem images without any medical information and deduced the immediate cause of death. Then, the anatomy instructor revealed the medical information available. Based on this information, the radiologist, anatomy instructor, and pathologists suggested candidate sampling sites for pathological examination. On the last day of the dissection period, the pathologists resected the sample tissues and processed them for pathological examination. In 12 of 33 cases, the presumed causes of death could be determined based on PMI alone, and revision of the cause of death described in the death certificate was considered in five (15.2%) cases, based on PMI and pathological analysis. This article presents a novel method of pathological analysis of cadavers for anatomical dissection using PMI without disturbing the anatomy education of medical students.
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spelling pubmed-68568642019-11-21 Pathological analysis of cadavers for educational dissection by using postmortem imaging Noriki, Sakon Iino, Satoshi Kinoshita, Kazuyuki Fukazawa, Yugo Inai, Kunihiro Sakai, Toyohiko Kimura, Hirohiko Pathol Int Original Articles This study was performed primarily to clarify whether pathological analysis of cadavers for anatomical dissection is possible using postmortem imaging (PMI), and whether this is worthwhile. A total of 33 cadavers that underwent systematic anatomical dissection at our medical school also underwent PMI. Fixative solution was injected into the corpus 3–4 days after death. PMI was then performed using an 8‐slice multi‐detector CT scanner 3 months before dissection. Before dissection, a conference was held to discuss the findings of the PMI. First, two radiologists read the postmortem images without any medical information and deduced the immediate cause of death. Then, the anatomy instructor revealed the medical information available. Based on this information, the radiologist, anatomy instructor, and pathologists suggested candidate sampling sites for pathological examination. On the last day of the dissection period, the pathologists resected the sample tissues and processed them for pathological examination. In 12 of 33 cases, the presumed causes of death could be determined based on PMI alone, and revision of the cause of death described in the death certificate was considered in five (15.2%) cases, based on PMI and pathological analysis. This article presents a novel method of pathological analysis of cadavers for anatomical dissection using PMI without disturbing the anatomy education of medical students. John Wiley and Sons Inc. 2019-10-20 2019-10 /pmc/articles/PMC6856864/ /pubmed/31631464 http://dx.doi.org/10.1111/pin.12857 Text en © 2019 The Authors. Pathology International published by Japanese Society of Pathology and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Noriki, Sakon
Iino, Satoshi
Kinoshita, Kazuyuki
Fukazawa, Yugo
Inai, Kunihiro
Sakai, Toyohiko
Kimura, Hirohiko
Pathological analysis of cadavers for educational dissection by using postmortem imaging
title Pathological analysis of cadavers for educational dissection by using postmortem imaging
title_full Pathological analysis of cadavers for educational dissection by using postmortem imaging
title_fullStr Pathological analysis of cadavers for educational dissection by using postmortem imaging
title_full_unstemmed Pathological analysis of cadavers for educational dissection by using postmortem imaging
title_short Pathological analysis of cadavers for educational dissection by using postmortem imaging
title_sort pathological analysis of cadavers for educational dissection by using postmortem imaging
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856864/
https://www.ncbi.nlm.nih.gov/pubmed/31631464
http://dx.doi.org/10.1111/pin.12857
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