The emerging role of long non-coding RNAs in tumor-associated macrophages

Tumor-associated macrophages (TAMs) are an important cellular component of the tumor microenvironment (TME) and play an essential role in tumor immunity. Recently, numerous studies have indicated that long non-coding RNAs (lncRNAs) can affect several functions of TAMs. In the present review, we summ...

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Detalles Bibliográficos
Autores principales: Han, Dafei, Fang, Yilong, Guo, Yawei, Hong, Wenming, Tu, Jiajie, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856883/
https://www.ncbi.nlm.nih.gov/pubmed/31777603
http://dx.doi.org/10.7150/jca.35770
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author Han, Dafei
Fang, Yilong
Guo, Yawei
Hong, Wenming
Tu, Jiajie
Wei, Wei
author_facet Han, Dafei
Fang, Yilong
Guo, Yawei
Hong, Wenming
Tu, Jiajie
Wei, Wei
author_sort Han, Dafei
collection PubMed
description Tumor-associated macrophages (TAMs) are an important cellular component of the tumor microenvironment (TME) and play an essential role in tumor immunity. Recently, numerous studies have indicated that long non-coding RNAs (lncRNAs) can affect several functions of TAMs. In the present review, we summarize the versatile role of lncRNAs in the polarization, epigenetic modulation, and classic signaling pathways of TAMs, which represent a potential target for tumor diagnosis or treatment.
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spelling pubmed-68568832019-11-27 The emerging role of long non-coding RNAs in tumor-associated macrophages Han, Dafei Fang, Yilong Guo, Yawei Hong, Wenming Tu, Jiajie Wei, Wei J Cancer Review Tumor-associated macrophages (TAMs) are an important cellular component of the tumor microenvironment (TME) and play an essential role in tumor immunity. Recently, numerous studies have indicated that long non-coding RNAs (lncRNAs) can affect several functions of TAMs. In the present review, we summarize the versatile role of lncRNAs in the polarization, epigenetic modulation, and classic signaling pathways of TAMs, which represent a potential target for tumor diagnosis or treatment. Ivyspring International Publisher 2019-10-22 /pmc/articles/PMC6856883/ /pubmed/31777603 http://dx.doi.org/10.7150/jca.35770 Text en © The author(s) This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Review
Han, Dafei
Fang, Yilong
Guo, Yawei
Hong, Wenming
Tu, Jiajie
Wei, Wei
The emerging role of long non-coding RNAs in tumor-associated macrophages
title The emerging role of long non-coding RNAs in tumor-associated macrophages
title_full The emerging role of long non-coding RNAs in tumor-associated macrophages
title_fullStr The emerging role of long non-coding RNAs in tumor-associated macrophages
title_full_unstemmed The emerging role of long non-coding RNAs in tumor-associated macrophages
title_short The emerging role of long non-coding RNAs in tumor-associated macrophages
title_sort emerging role of long non-coding rnas in tumor-associated macrophages
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856883/
https://www.ncbi.nlm.nih.gov/pubmed/31777603
http://dx.doi.org/10.7150/jca.35770
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