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Up-regulation of EMT-related gene VCAN by NPM1 mutant-driven TGF-β/cPML signalling promotes leukemia cell invasion

Acute myeloid leukemia (AML) with mutated nucleophosmin (NPM1) is acknowledged as a distinct leukemia entity in the 2016 updated World Health Organization (WHO) classification. NPM1-mutated AML patients are correlated with higher extramedullary involvement. Epithelial-mesenchymal transition (EMT) is...

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Detalles Bibliográficos
Autores principales:	Yang, Liyuan, Wang, Lu, Yang, Zailin, Jin, Hongjun, Zou, Qin, Zhan, Qian, Tang, Yuting, Tao, Yao, Lei, Li, Jing, Yipei, Jiang, Xueke, Zhang, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856892/ https://www.ncbi.nlm.nih.gov/pubmed/31777586 http://dx.doi.org/10.7150/jca.30223

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