Cargando…
Etomidate and propylene glycol activate nociceptive TRP ion channels
BACKGROUND: Etomidate is a preferred drug for the induction of general anesthesia in cardiovascular risk patients. As with propofol and other perioperatively used anesthetics, the application of aqueous etomidate formulations causes an intensive burning pain upon injection. Such algogenic properties...
Autores principales: | Niedermirtl, Florian, Eberhardt, Mirjam, Namer, Barbara, Leffler, Andreas, Nau, Carla, Reeh, Peter W, Kistner, Katrin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856977/ https://www.ncbi.nlm.nih.gov/pubmed/30345869 http://dx.doi.org/10.1177/1744806918811699 |
Ejemplares similares
-
Activation of TRPA1 by membrane permeable local anesthetics
por: Leffler, Andreas, et al.
Publicado: (2011) -
TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons
por: Eberhardt, Mirjam, et al.
Publicado: (2017) -
Formation of Water-Channel by Propylene Glycol into Polymer for Porous Materials
por: Hong, Seong Ho, et al.
Publicado: (2021) -
Reproductive toxicology. Propylene glycol.
Publicado: (1997) -
Nociceptive TRP Channels: Sensory Detectors and Transducers in Multiple Pain Pathologies
por: Mickle, Aaron D., et al.
Publicado: (2016)