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On-demand PEGylation and dePEGylation of PLA-based nanocarriers via amphiphilic mPEG-TK-Ce6 for nanoenabled cancer chemotherapy

Rationale: PEGylation of nanocarriers could extend blood circulation time and enhance tumor accumulation via the enhanced permeability and retention (EPR) effect. Unfortunately, the PEG moiety suppresses tumor cell internalization of nanocarriers, resulting in limited therapeutic efficiency (known a...

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Detalles Bibliográficos
Autores principales:	Zhu, Yueqiang, Chen, Chao, Cao, Ziyang, Shen, Song, Li, Laisheng, Li, Dongdong, Wang, Junxia, Yang, Xianzhu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857060/ https://www.ncbi.nlm.nih.gov/pubmed/31754398 http://dx.doi.org/10.7150/thno.37128

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