Pten loss in Lgr5(+) hair follicle stem cells promotes SCC development

Accumulating data support that tissue stem cells give rise to cancer cells. Hair follicle stem cells (HFSCs) undergo cyclic quiescence and activation and may sever as the origin of cutaneous squamous cell carcinoma (SCC). Pten is a tumor suppressor gene that is frequently mutated in hereditary cance...

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Detalles Bibliográficos
Autores principales: Chen, Haiyan, Wang, Xusheng, Chen, Yu, Han, Jimin, Kong, Deqiang, Zhu, Meishu, Fu, Xiaobing, Wu, Yaojiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857063/
https://www.ncbi.nlm.nih.gov/pubmed/31754399
http://dx.doi.org/10.7150/thno.35467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857063/
https://www.ncbi.nlm.nih.gov/pubmed/31754399
http://dx.doi.org/10.7150/thno.35467

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