Cargando…

Mesenchymal stem cell transplantation alleviates experimental Sjögren's syndrome through IFN-β/IL-27 signaling axis

Rationale: Although mesenchymal stem cell (MSC) transplantation has been proved to be an effective therapeutic approach to treat experimental Sjögren's syndrome (SS), the detailed underlying mechanisms remains unknown. IL-27 has diverse influences on the regulation of T cell differentiation and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yao, Genhong, Qi, Jingjing, Liang, Jun, Shi, Bingyu, Chen, Weiwei, Li, Wenchao, Tang, Xiaojun, Wang, Dandan, Lu, Liwei, Chen, Wanjun, Shi, Songtao, Hou, Yayi, Sun, Lingyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2019
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857067/ https://www.ncbi.nlm.nih.gov/pubmed/31754394 http://dx.doi.org/10.7150/thno.37351

Ejemplares similares

Mesenchymal stem cell transplantation ameliorates Sjögren’s syndrome via suppressing IL-12 production by dendritic cells
por: Shi, Bingyu, et al.
Publicado: (2018)

IL-27 Regulated CD4(+)IL-10(+) T Cells in Experimental Sjögren Syndrome
por: Qi, Jingjing, et al.
Publicado: (2020)

Umbilical cord mesenchymal stem cells alleviate Sjögren’s syndrome and related pulmonary inflammation through regulating Vγ4(+) IL-17(+) T cells
por: Cong, Yan, et al.
Publicado: (2022)

Mesenchymal stem cell transplantation alleviated atherosclerosis in systemic lupus erythematosus through reducing MDSCs
por: Yao, Genhong, et al.
Publicado: (2022)

Mesenchymal stem cells inhibited the differentiation of MDSCs via COX2/PGE2 in experimental sialadenitis
por: Qi, Jingjing, et al.
Publicado: (2020)

Interleukin-12 exacerbates Sjögren's syndrome through induction of myeloid-derived suppressor cells
por: Qi, Jingjing, et al.
Publicado: (2019)

Clearance of apoptotic cells by mesenchymal stem cells contributes to immunosuppression via PGE2
por: Zhang, Zhuoya, et al.
Publicado: (2019)

Mesenchymal stem cells prevent overwhelming inflammation and reduce infection severity via recruiting CXCR3(+) regulatory T cells
por: Li, Wenchao, et al.
Publicado: (2020)

Infection with Opportunistic Bacteria Triggers Severe Pulmonary Inflammation in Lupus-Prone Mice
por: Li, Wenchao, et al.
Publicado: (2019)

Mesenchymal Stem Cells Enhance Pulmonary Antimicrobial Immunity and Prevent Following Bacterial Infection
por: Li, Wenchao, et al.
Publicado: (2020)

A CD8 T Cell/Indoleamine 2,3-Dioxygenase Axis Is Required for Mesenchymal Stem Cell Suppression of Human Systemic Lupus Erythematosus
por: Wang, Dandan, et al.
Publicado: (2014)

Mesenchymal Stem Cells Control Complement C5 Activation by Factor H in Lupus Nephritis
por: Ma, Haijun, et al.
Publicado: (2018)

Mesenchymal stem cells alleviate experimental autoimmune cholangitis through immunosuppression and cytoprotective function mediated by galectin-9
por: Fan, Junyu, et al.
Publicado: (2018)

NK-DC crosstalk controls the autopathogenic Th17 response through an innate IFN-γ–IL-27 axis
por: Chong, Wai Po, et al.
Publicado: (2015)

Mesenchymal Stem Cells Promote the Osteogenesis in Collagen-Induced Arthritic Mice through the Inhibition of TNF-α
por: Liu, Chang, et al.
Publicado: (2018)

EP27 Sjögren’s or not: an anxious diagnosis
por: Nizam, Sharmin
Publicado: (2020)

Mesenchymal Stem Cell-Based Tissue Regeneration is Governed by Recipient T Lymphocyte via IFN-γ and TNF-α
por: Liu, Yi, et al.
Publicado: (2011)

Dendritic cell-derived IL-27 p28 regulates T cell program in pathogenicity and alleviates acute graft-versus-host disease
por: Gong, Huanle, et al.
Publicado: (2022)

Bridging Radiotherapy to Immunotherapy: The IFN–JAK–STAT Axis
por: Shi, Lewis Zhichang, et al.
Publicado: (2021)

Comprehensive expression profile of long non-coding RNAs in Peripheral blood mononuclear cells from patients with neuropsychiatric systemic lupus erythematosus
por: Geng, Linyu, et al.
Publicado: (2020)

Gene therapy using IL-27 ameliorates Sjögren's syndrome-like autoimmune exocrinopathy
por: Lee, Byung Ha, et al.
Publicado: (2012)

Serum IFN‐γ Predicts the Therapeutic Effect of Mesenchymal Stem Cells Transplantation in Systemic Lupus Erythematosus Patients
por: Wang, Dandan, et al.
Publicado: (2017)

Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure
por: Chen, Lu, et al.
Publicado: (2017)

IL-27 suppresses antimicrobial activity in human leprosy
por: Teles, Rosane M. B., et al.
Publicado: (2015)

Type I IFN Promotes IL-10 Production from T Cells to Suppress Th17 Cells and Th17-Associated Autoimmune Inflammation
por: Zhang, Lixia, et al.
Publicado: (2011)

Adipose-mesenchymal stromal cells suppress experimental Sjögren syndrome by IL-33-driven expansion of ST2(+) regulatory T cells
por: Liu, Ousheng, et al.
Publicado: (2021)

Identification of Interleukin-27 (IL-27)/IL-27 Receptor Subunit Alpha as a Critical Immune Axis for In Vivo HIV Control
por: Ruiz-Riol, M., et al.
Publicado: (2017)

Double Allogenic Mesenchymal Stem Cells Transplantations Could Not Enhance Therapeutic Effect Compared with Single Transplantation in Systemic Lupus Erythematosus
por: Wang, Dandan, et al.
Publicado: (2012)

Mesenchymal stem cell therapy induces FLT3L and CD1c(+) dendritic cells in systemic lupus erythematosus patients
por: Yuan, Xinran, et al.
Publicado: (2019)

The CREG1-FBXO27-LAMP2 axis alleviates diabetic cardiomyopathy by promoting autophagy in cardiomyocytes
por: Liu, Dan, et al.
Publicado: (2023)

Interleukin-27 Is Essential for Type 1 Diabetes Development and Sjögren Syndrome-like Inflammation
por: Ciecko, Ashley E., et al.
Publicado: (2019)

Interleukin-27 is essential for type 1 diabetes development and Sjögren syndrome-like inflammation
por: Ciecko, Ashley E., et al.
Publicado: (2021)

IL-27 Signaling Is Crucial for Survival of Mice Infected with African Trypanosomes via Preventing Lethal Effects of CD4(+) T Cells and IFN-γ
por: Liu, Gongguan, et al.
Publicado: (2015)

Type I IFN Induces IL-10 Production in an IL-27–Independent Manner and Blocks Responsiveness to IFN-γ for Production of IL-12 and Bacterial Killing in Mycobacterium tuberculosis–Infected Macrophages
por: McNab, Finlay W., et al.
Publicado: (2014)

IL-27 increases BST-2 expression in human monocytes and T cells independently of type I IFN
por: Guzzo, Christina, et al.
Publicado: (2012)

IL-27 induces an IFN-like signature in murine macrophages which in turn modulate colonic epithelium
por: Andrews, Caroline, et al.
Publicado: (2023)

Moxibustion alleviates depression-like behavior in rats with Crohn’s disease by inhibiting the kynurenine pathway metabolism in the gut-brain axis
por: Bao, Chunhui, et al.
Publicado: (2022)

The IL‐27/IL‐27R axis is altered in CD4(+) and CD8(+) T lymphocytes from multiple sclerosis patients
por: Clénet, Marie‐Laure, et al.
Publicado: (2021)

IL-21 and Sjögren's syndrome
por: Scofield, R Hal
Publicado: (2011)

IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT(+) HIVGag-specific T cells
por: Cheng, Jie, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_0fbv1bka2kodjinma0ese9k55o