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An unexpectedly high occurrence of aciclovir-induced neuropsychiatric symptoms in patients treated for herpesvirus CNS infection: a prospective observational study

BACKGROUND: Aciclovir is effective in herpesvirus infections of the CNS. Aciclovir-induced neuropsychiatric symptoms (AINS) have been reported and are associated with high CSF concentrations of aciclovir metabolite 9-carboxymethoxymethylguanine (CMMG). Risk factors except for renal failure have not...

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Detalles Bibliográficos
Autores principales: Lindström, Johan, Helldén, Anders, Lycke, Jan, Grahn, Anna, Studahl, Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857197/
https://www.ncbi.nlm.nih.gov/pubmed/31504577
http://dx.doi.org/10.1093/jac/dkz357