Atheroprotective effects of methotrexate via the inhibition of YAP/TAZ under disturbed flow

BACKGROUND: Atherosclerosis preferentially develops in regions of disturbed flow (DF). Emerging evidence indicates that yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ), which are both effectors of the Hippo pathway, sense different blood flow patterns and r...

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Detalles Bibliográficos
Autores principales: Liu, Dandan, Lv, Hang, Liu, Qi, Sun, Yanli, Hou, Shenglong, Zhang, Lu, Yang, Mengyue, Han, Baihe, wang, Gang, Wang, Xuedong, Du, Wenjuan, Nie, Honggang, Zhang, Ruoxi, Huang, Xingtao, Hou, Jingbo, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857284/
https://www.ncbi.nlm.nih.gov/pubmed/31730006
http://dx.doi.org/10.1186/s12967-019-02135-8

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