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Mesangial cells are key contributors to the fibrotic damage seen in the lupus nephritis glomerulus

BACKGROUND: Lupus nephritis (LN) affects up to 80% of juvenile-onset systemic lupus erythematosus patients. Mesangial cells (MCs) comprise a third of the glomerular cells and are key contributors to fibrotic changes within the kidney. This project aims to identify the roles of MCs in an in vitro mod...

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Detalles Bibliográficos
Autores principales: Wright, Rachael D., Dimou, Paraskevi, Northey, Sarah J., Beresford, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857320/
https://www.ncbi.nlm.nih.gov/pubmed/31807119
http://dx.doi.org/10.1186/s12950-019-0227-x