Tempol improves neuroinflammation and delays motor dysfunction in a mouse model (SOD1(G93A)) of ALS

BACKGROUND: The development of new therapeutic strategies to treat amyotrophic lateral sclerosis (ALS) is of utmost importance. The use of cyclic nitroxides such as tempol may provide neuroprotection and improve lifespan. We investigated whether tempol (50 mg/kg) presents therapeutic potential in SO...

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Detalles Bibliográficos
Autores principales: Chiarotto, Gabriela Bortolança, Cartarozzi, Luciana Politti, Perez, Matheus, Biscola, Natalia Perussi, Spejo, Aline Barroso, Gubert, Fernanda, França Junior, Marcondes, Mendez-Otero, Rosália, de Oliveira, Alexandre Leite Rodrigues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857328/
https://www.ncbi.nlm.nih.gov/pubmed/31727149
http://dx.doi.org/10.1186/s12974-019-1598-x

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