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PPAR-γ promotes p38 MAP kinase-mediated endothelial cell permeability through activating Sirt3

BACKGROUND: Ischemia-reperfusion (I/R)-induced vascular dysfunction is the main factor to acute ischemic stroke. Sirt3 is one of the sirtuin family members, which plays an important role in the development of neurological diseases. METHODS: In this study, we constructed I/R injury model on HBMEC cel...

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Detalles Bibliográficos
Autores principales:	Zhao, Zhenzhen, Zhang, Xiaoxiu, Dai, Yuanqiang, Pan, Ke, Deng, Yu, Meng, Yan, Xu, Tao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857342/ https://www.ncbi.nlm.nih.gov/pubmed/31729962 http://dx.doi.org/10.1186/s12883-019-1508-y

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