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Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital
BACKGROUND: The prevalence of anemia increases with age. Some serious underlying conditions may lead to anemia in the old age. The present study was undertaken to detect and do morphological typing of anemia and further delineate etiological factors in elderly patients. METHODS: In this hospital-bas...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857363/ https://www.ncbi.nlm.nih.gov/pubmed/31742166 http://dx.doi.org/10.4103/jfmpc.jfmpc_668_19 |
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author | Raisinghani, Nitin Kumar, Sunil Acharya, Sourya Gadegone, Aditi Pai, Vinay |
author_facet | Raisinghani, Nitin Kumar, Sunil Acharya, Sourya Gadegone, Aditi Pai, Vinay |
author_sort | Raisinghani, Nitin |
collection | PubMed |
description | BACKGROUND: The prevalence of anemia increases with age. Some serious underlying conditions may lead to anemia in the old age. The present study was undertaken to detect and do morphological typing of anemia and further delineate etiological factors in elderly patients. METHODS: In this hospital-based prevalence study carried out a tertiary care center over one and half years, a total of 90 patients were fully evaluated for etiology and typing of anemia in elderly (>60 years age) patients. Details of other significant medical and surgical history were noted. Laboratory investigations were conducted, which included complete hemogram, peripheral blood smear, reticulocyte count, erythrocyte sedimentation rate estimation, serum urea, serum creatinine and serum lactate dehydrogenase, bone marrow examination (with Prussian blue marrow iron staining), serum iron and serum total iron-binding capacity, serum ferritin, and stool and urine examination. RESULTS: The mean hemoglobin as per age was 60–64 years- 5.95 gm%, 65–69 years - 6.7 gm%, 70–74 years - 6.58 gm%, and 75–79 years - 6.87 gm%. The difference not being significant (p = 0.33). Morphologically, 53 patients (24 males and 29 females) had microcytic anemia, 27 (17 males and 10 females) had normocytic anemia, and 10 (8 males and 2 females) had macrocytic anemia. Anemia of chronic disease (ACD) was the most common occurrence (50, 55.56%), followed by iron deficiency anemia (IDA) (27, 30%), macrocytic anemia (9, 10%), and others 4 (4.44%). The cause of anemia was found in 10 out of 27 (37.03%) patients in the IDA group, 28 out of 50 (56%) in the ACD group, whereas the etiology was discernible in only one out of nine cases (11.1%) of macrocytic anemias. CONCLUSION: There was no significant difference observed in the mean hemoglobin levels as the age increased. Morphologically, the majority of the patients had microcytic anemia, followed by normocytic anemia. A population-based study is recommended for further assessment of the prevalence and causes of anemias in asymptomatic elderly subjects. |
format | Online Article Text |
id | pubmed-6857363 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-68573632019-11-18 Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital Raisinghani, Nitin Kumar, Sunil Acharya, Sourya Gadegone, Aditi Pai, Vinay J Family Med Prim Care Original Article BACKGROUND: The prevalence of anemia increases with age. Some serious underlying conditions may lead to anemia in the old age. The present study was undertaken to detect and do morphological typing of anemia and further delineate etiological factors in elderly patients. METHODS: In this hospital-based prevalence study carried out a tertiary care center over one and half years, a total of 90 patients were fully evaluated for etiology and typing of anemia in elderly (>60 years age) patients. Details of other significant medical and surgical history were noted. Laboratory investigations were conducted, which included complete hemogram, peripheral blood smear, reticulocyte count, erythrocyte sedimentation rate estimation, serum urea, serum creatinine and serum lactate dehydrogenase, bone marrow examination (with Prussian blue marrow iron staining), serum iron and serum total iron-binding capacity, serum ferritin, and stool and urine examination. RESULTS: The mean hemoglobin as per age was 60–64 years- 5.95 gm%, 65–69 years - 6.7 gm%, 70–74 years - 6.58 gm%, and 75–79 years - 6.87 gm%. The difference not being significant (p = 0.33). Morphologically, 53 patients (24 males and 29 females) had microcytic anemia, 27 (17 males and 10 females) had normocytic anemia, and 10 (8 males and 2 females) had macrocytic anemia. Anemia of chronic disease (ACD) was the most common occurrence (50, 55.56%), followed by iron deficiency anemia (IDA) (27, 30%), macrocytic anemia (9, 10%), and others 4 (4.44%). The cause of anemia was found in 10 out of 27 (37.03%) patients in the IDA group, 28 out of 50 (56%) in the ACD group, whereas the etiology was discernible in only one out of nine cases (11.1%) of macrocytic anemias. CONCLUSION: There was no significant difference observed in the mean hemoglobin levels as the age increased. Morphologically, the majority of the patients had microcytic anemia, followed by normocytic anemia. A population-based study is recommended for further assessment of the prevalence and causes of anemias in asymptomatic elderly subjects. Wolters Kluwer - Medknow 2019-10-31 /pmc/articles/PMC6857363/ /pubmed/31742166 http://dx.doi.org/10.4103/jfmpc.jfmpc_668_19 Text en Copyright: © 2019 Journal of Family Medicine and Primary Care http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Raisinghani, Nitin Kumar, Sunil Acharya, Sourya Gadegone, Aditi Pai, Vinay Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title | Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title_full | Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title_fullStr | Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title_full_unstemmed | Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title_short | Does aging have an impact on hemoglobin? Study in elderly population at rural teaching hospital |
title_sort | does aging have an impact on hemoglobin? study in elderly population at rural teaching hospital |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857363/ https://www.ncbi.nlm.nih.gov/pubmed/31742166 http://dx.doi.org/10.4103/jfmpc.jfmpc_668_19 |
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