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Simvastatin Improves Neutrophil Function and Clinical Outcomes in Pneumonia. A Pilot Randomized Controlled Clinical Trial
Rationale: Population studies suggest improved sepsis outcomes with statins, but the results of randomized controlled trials in patients with sepsis and organ dysfunction in critical care settings have broadly been negative. In vitro data suggest that statins modulate age-related neutrophil function...
Autores principales: | Sapey, Elizabeth, Patel, Jaimin M., Greenwood, Hannah, Walton, Georgia M., Grudzinska, Frances, Parekh, Dhruv, Mahida, Rahul Y., Dancer, Rachel C. A., Lugg, Sebastian T., Howells, Philip A., Hazeldine, Jon, Newby, Paul, Scott, Aaron, Nightingale, Peter, Hill, Adam T., Thickett, David R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Thoracic Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857486/ https://www.ncbi.nlm.nih.gov/pubmed/31206313 http://dx.doi.org/10.1164/rccm.201812-2328OC |
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