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Case for diagnosis. Diffuse ulcerated nodular lesions()()

Langerhans cell histiocytosis is a rare clonal proliferative disease, characterized by the infiltration of one or multiple organs by histiocytes. Due to the diversity of signs and symptoms, the diagnosis of this disease is often late. The estimated incidence in adults is one to two cases per million...

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Autores principales: Martins, Paulo Henrique Teixeira, Dallagnese, Gabriela, Luzzatto, Laura, Dantas, Manuela Lima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857547/
https://www.ncbi.nlm.nih.gov/pubmed/31777366
http://dx.doi.org/10.1016/j.abd.2019.09.021
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author Martins, Paulo Henrique Teixeira
Dallagnese, Gabriela
Luzzatto, Laura
Dantas, Manuela Lima
author_facet Martins, Paulo Henrique Teixeira
Dallagnese, Gabriela
Luzzatto, Laura
Dantas, Manuela Lima
author_sort Martins, Paulo Henrique Teixeira
collection PubMed
description Langerhans cell histiocytosis is a rare clonal proliferative disease, characterized by the infiltration of one or multiple organs by histiocytes. Due to the diversity of signs and symptoms, the diagnosis of this disease is often late. The estimated incidence in adults is one to two cases per million, but the disease is probably underdiagnosed in this population. This report presents a case of disseminated Langerhans cell histiocytosis. The authors highlight the most characteristic aspects of this rare and heterogeneous disease, which usually presents as a challenging clinical diagnosis.
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spelling pubmed-68575472019-11-21 Case for diagnosis. Diffuse ulcerated nodular lesions()() Martins, Paulo Henrique Teixeira Dallagnese, Gabriela Luzzatto, Laura Dantas, Manuela Lima An Bras Dermatol What is your Diagnosis? Langerhans cell histiocytosis is a rare clonal proliferative disease, characterized by the infiltration of one or multiple organs by histiocytes. Due to the diversity of signs and symptoms, the diagnosis of this disease is often late. The estimated incidence in adults is one to two cases per million, but the disease is probably underdiagnosed in this population. This report presents a case of disseminated Langerhans cell histiocytosis. The authors highlight the most characteristic aspects of this rare and heterogeneous disease, which usually presents as a challenging clinical diagnosis. Sociedade Brasileira de Dermatologia 2019 2019-09-30 /pmc/articles/PMC6857547/ /pubmed/31777366 http://dx.doi.org/10.1016/j.abd.2019.09.021 Text en © 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle What is your Diagnosis?
Martins, Paulo Henrique Teixeira
Dallagnese, Gabriela
Luzzatto, Laura
Dantas, Manuela Lima
Case for diagnosis. Diffuse ulcerated nodular lesions()()
title Case for diagnosis. Diffuse ulcerated nodular lesions()()
title_full Case for diagnosis. Diffuse ulcerated nodular lesions()()
title_fullStr Case for diagnosis. Diffuse ulcerated nodular lesions()()
title_full_unstemmed Case for diagnosis. Diffuse ulcerated nodular lesions()()
title_short Case for diagnosis. Diffuse ulcerated nodular lesions()()
title_sort case for diagnosis. diffuse ulcerated nodular lesions()()
topic What is your Diagnosis?
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857547/
https://www.ncbi.nlm.nih.gov/pubmed/31777366
http://dx.doi.org/10.1016/j.abd.2019.09.021
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