Reciprocal interactions between mtDNA and lifespan control in budding yeast

Loss of mitochondrial DNA (mtDNA) results in loss of mitochondrial respiratory activity, checkpoint-regulated inhibition of cell cycle progression, defects in growth, and nuclear genome instability. However, after several generations, yeast cells can adapt to the loss of mtDNA. During this adaptatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Garcia, Enrique J., de Jonge, Janeska J., Liao, Pin-Chao, Stivison, Elizabeth, Sing, Cierra N., Higuchi-Sanabria, Ryo, Boldogh, Istvan R., Pon, Liza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857569/
https://www.ncbi.nlm.nih.gov/pubmed/31599702
http://dx.doi.org/10.1091/mbc.E18-06-0356

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857569/
https://www.ncbi.nlm.nih.gov/pubmed/31599702
http://dx.doi.org/10.1091/mbc.E18-06-0356

Ejemplares similares