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Reciprocal interactions between mtDNA and lifespan control in budding yeast

Loss of mitochondrial DNA (mtDNA) results in loss of mitochondrial respiratory activity, checkpoint-regulated inhibition of cell cycle progression, defects in growth, and nuclear genome instability. However, after several generations, yeast cells can adapt to the loss of mtDNA. During this adaptatio...

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Detalles Bibliográficos
Autores principales: Garcia, Enrique J., de Jonge, Janeska J., Liao, Pin-Chao, Stivison, Elizabeth, Sing, Cierra N., Higuchi-Sanabria, Ryo, Boldogh, Istvan R., Pon, Liza A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857569/
https://www.ncbi.nlm.nih.gov/pubmed/31599702
http://dx.doi.org/10.1091/mbc.E18-06-0356

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