Cargando…
Phenome-wide Mendelian-randomization study of genetically determined vitamin D on multiple health outcomes using the UK Biobank study
BACKGROUND: Vitamin D deficiency is highly prevalent across the globe. Existing studies suggest that a low vitamin D level is associated with more than 130 outcomes. Exploring the causal role of vitamin D in health outcomes could support or question vitamin D supplementation. METHODS: We carried out...
Autores principales: | Meng, Xiangrui, Li, Xue, Timofeeva, Maria N, He, Yazhou, Spiliopoulou, Athina, Wei, Wei-Qi, Gifford, Aliya, Wu, Hongjiang, Varley, Timothy, Joshi, Peter, Denny, Joshua C, Farrington, Susan M, Zgaga, Lina, Dunlop, Malcolm G, McKeigue, Paul, Campbell, Harry, Theodoratou, Evropi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857754/ https://www.ncbi.nlm.nih.gov/pubmed/31518429 http://dx.doi.org/10.1093/ije/dyz182 |
Ejemplares similares
-
Genetically determined serum urate levels and cardiovascular and other diseases in UK Biobank cohort: A phenome-wide mendelian randomization study
por: Li, Xue, et al.
Publicado: (2019) -
Effects of body mass index on relationship status, social contact and socio-economic position: Mendelian randomization and within-sibling study in UK Biobank
por: Howe, Laura D, et al.
Publicado: (2019) -
A phenome-wide association study of a lipoprotein-associated phospholipase A(2) loss-of-function variant in 90 000 Chinese adults
por: Millwood, Iona Y, et al.
Publicado: (2016) -
MR-PheWAS: exploring the causal effect of SUA level on multiple disease outcomes by using genetic instruments in UK Biobank
por: Li, Xue, et al.
Publicado: (2018) -
The genetic interplay between body mass index, breast size and breast cancer risk: a Mendelian randomization analysis
por: Ooi, Brandon Nick Sern, et al.
Publicado: (2019)