Transcriptome-based molecular staging of human stem cell-derived retinal organoids uncovers accelerated photoreceptor differentiation by 9-cis retinal

Purpose: Retinal organoids generated from human pluripotent stem cells exhibit considerable variability during differentiation. Our goals are to assess developmental maturity of the neural retina in vitro and design improved protocols based on objective criteria. Methods: We performed transcriptome...

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Detalles Bibliográficos
Autores principales: Kaya, Koray D., Chen, Holly Y., Brooks, Matthew J., Kelley, Ryan A., Shimada, Hiroko, Nagashima, Kunio, de Val, Natalia, Drinnan, Charles T., Gieser, Linn, Kruczek, Kamil, Erceg, Slaven, Li, Tiansen, Lukovic, Dunja, Adlakha, Yogita K., Welby, Emily, Swaroop, Anand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857775/
https://www.ncbi.nlm.nih.gov/pubmed/31814692

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