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Dynamic UTR Usage Regulates Alternative Translation to Modulate Gap Junction Formation during Stress and Aging
Connexin43 (Cx43; gene name GJA1) is the most ubiquitously expressed gap junction protein, and understanding of its regulation largely falls under transcription and post-translational modification. In addition to Cx43, Gja1 mRNA encodes internally translated isoforms regulating gap junction formatio...
Autores principales: | Zeitz, Michael J., Calhoun, Patrick J., James, Carissa C., Taetzsch, Thomas, George, Kijana K., Robel, Stefanie, Valdez, Gregorio, Smyth, James W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6857847/ https://www.ncbi.nlm.nih.gov/pubmed/31141695 http://dx.doi.org/10.1016/j.celrep.2019.04.114 |
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