Type I Interferon Predicts an Alternate Immune System Phenotype in Systemic Lupus Erythematosus

OBJECTIVE: Type I interferon (IFN) is important to systemic lupus erythematosus (SLE) pathogenesis, but it is not clear how chronic elevations in IFN alter immune function. We compared cytokine responses after whole blood stimulation with Toll‐like receptor (TLR) agonists in high‐ and low‐IFN SLE pa...

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Detalles Bibliográficos
Autores principales: Thanarajasingam, Uma, Muppirala, Anoohya N., Jensen, Mark A., Ghodke‐Puranik, Yogita, Dorschner, Jessica M., Vsetecka, Danielle M., Amin, Shreyasee, Makol, Ashima, Ernste, Floranne, Osborn, Thomas, Moder, Kevin, Chowdhary, Vaidehi, Niewold, Timothy B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858011/
https://www.ncbi.nlm.nih.gov/pubmed/31777831
http://dx.doi.org/10.1002/acr2.11073

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