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Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer
Chronic inflammation and chromosome aneuploidy are major traits of primary liver cancer (PLC), which represent the second most common cause of cancer-related death worldwide. Increased cancer fitness and aggressiveness of PLC may be achieved by enhancing tumoral genomic complexity that alters tumor...
Autores principales: | Kwon, So Mee, Budhu, Anuradha, Woo, Hyun Goo, Chaisaingmongkol, Jittiporn, Dang, Hien, Forgues, Marshonna, Harris, Curtis C., Zhang, Gao, Auslander, Noam, Ruppin, Eytan, Mahidol, Chulabhorn, Ruchirawat, Mathuros, Wang, Xin Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858353/ https://www.ncbi.nlm.nih.gov/pubmed/31729408 http://dx.doi.org/10.1038/s41598-019-52578-8 |
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