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PTBP1-mediated regulation of AXL mRNA stability plays a role in lung tumorigenesis

AXL is expressed in many types of cancer and promotes cancer cell survival, metastasis and drug resistance. Here, we focus on identifying modulators that regulate AXL at the mRNA level. We have previously observed that the AXL promoter activity is inversely correlated with the AXL expression levels,...

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Detalles Bibliográficos
Autores principales:	Cho, Chun-Yu, Chung, Shih-Ying, Lin, Shankung, Huang, Jhy-Shrian, Chen, Yen-Lin, Jiang, Shih-Sheng, Cheng, Li-Chun, Kuo, Tsu-Hsiang, Lay, Jong-Ding, Yang, Ya-Yu, Lai, Gi-Ming, Chuang, Shuang-En
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858377/ https://www.ncbi.nlm.nih.gov/pubmed/31729427 http://dx.doi.org/10.1038/s41598-019-53097-2

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