mTORC1 activity is essential for erythropoiesis and B cell lineage commitment

Mechanistic target of rapamycin (mTOR) is a serine/threonine protein kinase that mediates phosphoinositide-3-kinase (PI3K)/AKT signalling. This pathway is involved in a plethora of cellular functions including protein and lipid synthesis, cell migration, cell proliferation and apoptosis. In this stu...

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Detalles Bibliográficos
Autores principales: Malik, Natasha, Dunn, Karen M., Cassels, Jennifer, Hay, Jodie, Estell, Christopher, Sansom, Owen J., Michie, Alison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858379/
https://www.ncbi.nlm.nih.gov/pubmed/31729420
http://dx.doi.org/10.1038/s41598-019-53141-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858379/
https://www.ncbi.nlm.nih.gov/pubmed/31729420
http://dx.doi.org/10.1038/s41598-019-53141-1

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