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Pharmacokinetics of Azithromycin, Levofloxacin, and Ofloxacin in Rabbit Extraocular Tissues After Ophthalmic Administration
INTRODUCTION: Azithromycin demonstrates high tissue distribution and prolonged elimination half-life. In this study, we monitored the pharmacokinetics of a single ophthalmic administration of 1% azithromycin ophthalmic solution containing polycarbophil in the extraocular tissues, including the eyeli...
Autores principales: | Sakai, Tatsuya, Shinno, Keisuke, Kurata, Masaaki, Kawamura, Akio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858417/ https://www.ncbi.nlm.nih.gov/pubmed/31372937 http://dx.doi.org/10.1007/s40123-019-00205-0 |
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