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Virus-borne mini-CRISPR arrays are involved in interviral conflicts

CRISPR-Cas immunity is at the forefront of antivirus defense in bacteria and archaea and specifically targets viruses carrying protospacers matching the spacers catalogued in the CRISPR arrays. Here, we perform deep sequencing of the CRISPRome—all spacers contained in a microbiome—associated with hy...

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Detalles Bibliográficos
Autores principales: Medvedeva, Sofia, Liu, Ying, Koonin, Eugene V., Severinov, Konstantin, Prangishvili, David, Krupovic, Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858448/
https://www.ncbi.nlm.nih.gov/pubmed/31729390
http://dx.doi.org/10.1038/s41467-019-13205-2

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