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Virus-borne mini-CRISPR arrays are involved in interviral conflicts
CRISPR-Cas immunity is at the forefront of antivirus defense in bacteria and archaea and specifically targets viruses carrying protospacers matching the spacers catalogued in the CRISPR arrays. Here, we perform deep sequencing of the CRISPRome—all spacers contained in a microbiome—associated with hy...
Autores principales: | Medvedeva, Sofia, Liu, Ying, Koonin, Eugene V., Severinov, Konstantin, Prangishvili, David, Krupovic, Mart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858448/ https://www.ncbi.nlm.nih.gov/pubmed/31729390 http://dx.doi.org/10.1038/s41467-019-13205-2 |
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