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Rpd3L and Hda1 histone deacetylases facilitate repair of broken forks by promoting sister chromatid cohesion

Genome stability involves accurate replication and DNA repair. Broken replication forks, such as those encountering a nick, lead to double strand breaks (DSBs), which are preferentially repaired by sister-chromatid recombination (SCR). To decipher the role of chromatin in eukaryotic DSB repair, here...

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Detalles Bibliográficos
Autores principales: Ortega, Pedro, Gómez-González, Belén, Aguilera, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858524/
https://www.ncbi.nlm.nih.gov/pubmed/31729385
http://dx.doi.org/10.1038/s41467-019-13210-5