Profiling the mouse brain endothelial transcriptome in health and disease models reveals a core blood-brain barrier dysfunction module

Blood vessels in the central nervous system (CNS) form a specialized and critical structure, the blood-brain barrier (BBB). We present a resource to understand the molecular mechanisms that regulate BBB function in health and dysfunction during disease. Using endothelial cell enrichment and RNA sequ...

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Detalles Bibliográficos
Autores principales: Munji, Roeben Nocon, Soung, Allison Luen, Weiner, Geoffrey Aaron, Sohet, Fabien, Semple, Bridgette Deanne, Trivedi, Alpa, Gimlin, Kayleen, Kotoda, Masakazu, Korai, Masaaki, Aydin, Sidar, Batugal, Austin, Cabangcala, Anne Christelle, Schupp, Patrick Georg, Oldham, Michael Clark, Hashimoto, Tomoki, Noble-Haeusslein, Linda J., Daneman, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858546/
https://www.ncbi.nlm.nih.gov/pubmed/31611708
http://dx.doi.org/10.1038/s41593-019-0497-x

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