HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype

Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine single nucleotide polymorphisms (SNPs) associated with the extent of abdominal (AAC, n = 9,417) or descending thoracic (TAC, n = 8,422) aortic...

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Detalles Bibliográficos
Autores principales: Malhotra, Rajeev, Mauer, Andreas C., Cardenas, Christian L. Lino, Guo, Xiuqing, Yao, Jie, Zhang, Xiaoling, Wunderer, Florian, Smith, Albert V., Wong, Quenna, Pechlivanis, Sonali, Hwang, Shih-Jen, Wang, Judy, Lu, Lingyi, Nicholson, Christopher J., Shelton, Georgia, Buswell, Mary D., Barnes, Hanna J., Sigurslid, Haakon H., Slocum, Charles, O’Rourke, Caitlin, Rhee, David K., Bagchi, Aranya, Nigwekar, Sagar U., Buys, Emmanuel S., Campbell, Catherine Y., Harris, Tamara, Budoff, Matthew, Criqui, Michael H., Rotter, Jerome I., Johnson, Andrew D., Song, Ci, Franceschini, Nora, Debette, Stephanie, Hoffmann, Udo, Kälsch, Hagen, Nöthen, Markus M., Sigurdsson, Sigurdur, Freedman, Barry I., Bowden, Donald W., Jöckel, Karl-Heinz, Moebus, Susanne, Erbel, Raimund, Feitosa, Mary F., Gudnason, Vilmundur, Thanassoulis, George, Zapol, Warren M., Lindsay, Mark E., Bloch, Donald B., Post, Wendy S., O’Donnell, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858575/
https://www.ncbi.nlm.nih.gov/pubmed/31659325
http://dx.doi.org/10.1038/s41588-019-0514-8

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