Exercise reduces inflammatory cell production and cardiovascular inflammation via instruction of hematopoietic progenitor cells

A sedentary lifestyle, chronic inflammation and leukocytosis propel atherosclerosis; however, it remains unclear if regular physical activity influences leukocyte production. Here we show that voluntary running decreases hematopoietic activity in mice. Exercise protects mice and humans with atherosc...

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Detalles Bibliográficos
Autores principales: Frodermann, Vanessa, Rohde, David, Courties, Gabriel, Severe, Nicolas, Schloss, Maximilian J., Amatullah, Hajera, McAlpine, Cameron S., Cremer, Sebastian, Hoyer, Friedrich F., Ji, Fei, van Koeverden, Ian D., Herisson, Fanny, Honold, Lisa, Masson, Gustavo Santos, Zhang, Shuang, Grune, Jana, Iwamoto, Yoshiko, Schmidt, Stephen P., Wojtkiewicz, Gregory R., Lee, I-Hsiu, Gustafsson, Karin, Pasterkamp, Gerard, de Jager, Saskia C.A., Sadreyev, Ruslan I., MacFadyen, Jean, Libby, Peter, Ridker, Paul, Scadden, David T., Naxerova, Kamila, Jeffrey, Kate L., Swirski, Filip K., Nahrendorf, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858591/
https://www.ncbi.nlm.nih.gov/pubmed/31700184
http://dx.doi.org/10.1038/s41591-019-0633-x

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