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β-TrCP-mediated ubiquitination and degradation of Dlg5 regulates hepatocellular carcinoma cell proliferation

BACKGROUND: Discs large homolog 5 (Dlg5) is a member of the membrane-associated guanylate kinase (MAGUK) adaptor family of proteins and its deregulation has been implicated in the malignancy of several cancer types. Dlg5 was down-regulated in hepatocellular carcinoma (HCC) and lower Dlg5 expression...

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Detalles Bibliográficos
Autores principales:	Wang, Dongping, Zhang, Qi, Li, Fenfen, Wang, Chan, Yang, Changming, Yu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858669/ https://www.ncbi.nlm.nih.gov/pubmed/31787846 http://dx.doi.org/10.1186/s12935-019-1029-1

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