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Highly versatile cancer photoimmunotherapy using photosensitizer-conjugated avidin and biotin-conjugated targeting antibodies

BACKGROUND: Photoimmunotherapy (PIT) employing antibody-photosensitizer conjugates is a promising treatment for cancer. However, the fixed antigen specificity severely limits the efficacy and the applicability. Here we describe a universal strategy for PIT of cancer by using a near-infrared (NIR) ph...

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Detalles Bibliográficos
Autores principales:	Shirasu, Naoto, Shibaguchi, Hirotomo, Yamada, Hiromi, Kuroki, Masahide, Yasunaga, Shin’ichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858743/ https://www.ncbi.nlm.nih.gov/pubmed/31787847 http://dx.doi.org/10.1186/s12935-019-1034-4

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