Overexpression of Tripartite Motif-Containing 48 (TRIM48) Inhibits Growth of Human Glioblastoma Cells by Suppressing Extracellular Signal Regulated Kinase 1/2 (ERK1/2) Pathway

BACKGROUND: Herein, we found that tripartite motif-containing 48 (TRIM48) was reduced in human glioblastoma (GBM) cell lines. We investigated whether and how TRIM48 functions in human GBM in vitro. MATERIAL/METHODS: Human GBM cells (U87 MG and U138 MG) were infected with lentivirus to overexpress TR...

Descripción completa

Detalles Bibliográficos
Autores principales: Xue, Li-ping, Lu, Bin, Gao, Bi-bo, Shi, Yang-yang, Xu, Jing-qi, Yang, Rui, Xu, Bo, Ding, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2019
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858785/
https://www.ncbi.nlm.nih.gov/pubmed/31703057
http://dx.doi.org/10.12659/MSM.916024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6858785/
https://www.ncbi.nlm.nih.gov/pubmed/31703057
http://dx.doi.org/10.12659/MSM.916024

Ejemplares similares